LECTURE TITLE: LEVERAGING TISSUE MICROENVIRONMENT TO SUPPRESS CANCER

Speaker: Prof. Marcin Iwanicki, PhD (Stevens Institute of Technology, New Jersey)

Prof. Marcin Iwaninki doctoral studies, at the University of Virginia supported by National Institute of Health Training Grant, were focused on the development of live light-emitting probes and microscopy technologies to study cell migration. During post-doctoral training, supported by National Cancer Institute Grant and philanthropy, at Harvard Medical School in the laboratory of Dr. Joan Brugge, Prof. Marcin Iwaninki accumulated in-depth knowledge of cancer biology and 3D culture systems. Specifically, through the collaborations with ovarian cancer physician-scientist at Brigham and Women Hospital, Dana-Farber Cancer Institute, and Massachusetts General Hospital, Prof. Marcin Iwaninki has successfully integrated 3D models of ovarian cancer with high-resolution live-cell imaging. Through the development of these methodologies, he has discovered the phenomenon of ovarian cancer mesothelial clearance and its dependence on mutant p53 and mesenchymal transcriptional programs. These studies have underscored the importance of the application of imaging technologies to ovarian cancer research.

In 2018, he was recruited to the Stevens Institute of Technology, Chemistry, Chemical Biology, and Bioengineering Department. While at Stevens, with the support of National Institute of Health, Kaleidoscope of Hope Ovarian Cancer Foundation and OLIPASS Inc, he has inaugurated a research program focused on the pathology-guided reconstruction of OC metastatic processes in the context of extracellular matrix, osmolyte microenvironment and chemotherapy recovery, for a better understanding of the recurrent disease. Prof. Marcin Iwaninki has been a recipient of Ovarian Cancer Action fellowship from United Kingdom and Marsha Rivkin Center for Ovarian Cancer Research, Scholar-in-Training Award. He routinely serves on National Cancer Institute study sections and is an associate editor for Frontiers Cancer Biology.

General information about the lecture:

Ovarian cancer (OC) recurs due to the ability of cancer cells to return to growth after chemotherapy is completed. So, there is a pressing need to develop safe and well-tolerated approaches that can continue to suppress tumor growth after treatment. I will present unexpected results, that taurine, an amino acid, and natural part of the human body metabolism, reactivates tumor suppression to control OC growth. Taurine should be readily available, as a part of treatment, due to its use as a dietary supplement.

Time: 21st June 2022, 12.00 p.m.
Place: Centrum Kongresowo-Dydaktyczne, sala A, Przybyszewskiego 37a

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